The conflict begins in the year when Miguel O'Hara (Spider-Man 2099) discovers that Alchemax scientist Walker Sloan has built a time machine. Sloan's goal is to travel back to the 1970s and found Alchemax decades early, ensuring it becomes a global monopoly and wipes out all competition.
As Sloan alters history, Miguel is temporarily trapped between dimensions. He witnesses a horrifying vision: his predecessor, , being killed in the past by a rampaging Anti-Venom . A Chronal Connection Spider-Man - Edge Of Time
A monstrous final boss created from the fusion of Anti-Venom, Walker Sloan, and Doctor Octopus. The conflict begins in the year when Miguel
In an altered 2099, a version of Peter Parker has become the CEO of Alchemax, attempting to rewrite history for his own misguided reasons. He witnesses a horrifying vision: his predecessor, ,
Controlled by Sloan, he is the immediate threat to Peter's life.
Ultimately, the two heroes must reconcile their different philosophies—Miguel's focus on the "big picture" of the future versus Peter's refusal to let anyone die—to fix the timeline and ensure both their worlds survive.